Vitamin C as an anti aging agent

Vitamin C is one of the most widely used skin care ingredients. The variety of skin rejuvenation / anti-wrinkle products with vitamin C is staggering. Do these products work? Do their claims have any substance? The situation is a little complicated. On one hand, vitamin C does possess definite, scientifically validated merits for wrinkle reduction and skin rejuvenation. On the other hand, many vitamin C products do not work.

Potentially, vitamin C can benefit skin in two important ways. Firstly, vitamin C is essential for the synthesis of collagen, a key structural protein of the skin. Adding vitamin C to a culture of skin cells (fibroblasts) dramatically increases the synthesis of collagen. Secondly, vitamin C is an antioxidant and can help reduce skin damage caused by free radicals. So, when vitamin C is properly delivered into skin cells, there is a good chance to reduce wrinkles and improve skin texture.

There are, however, some complicating circumstances often disregarded by manufacturers. First, vitamin C is relatively unstable (unless it is in a dry form). In the presence of air or other oxidizing agents, vitamin C is easily converted to oxidized forms. The oxidized vitamin C is not only incapable of boosting collagen synthesis or scavenging free radicals but may actually promote free radical formation causing damage to vital molecules such as proteins and DNA. In poorly prepared or poorly stored skin care products, vitamin C may already be oxidized by the time you apply it to your skin. Second, only highly concentrated preparations (10% or more) deliver enough vitamin C to the cells to be topically effective.

A number of skin care companies offer highly concentrated stabilized vitamin C products, which (at least in theory) are supposed to be consistently effective. However, these products are usually quite expensive. Furthermore, even stabilized vitamin C products may be at least somewhat oxidized by the time you use them. When vitamin C oxidizes, it eventually acquires a yellowish tint indicating an advanced stage of oxidation. Interestingly, some manufacturers add coloring to their vitamin C products, in which case it becomes hard to spot advanced vitamin C oxidation. Whatever the motives for adding color may be, we recommend avoiding vitamin C products that aren't colorless or white. Unfortunately, the lack of a tint does not, by itself, guarantee the lack of oxidation because the initial product of vitamin C oxidation (dehydroascorbic acid) is colorless. Only further oxidation produces a noticeable yellowish tint. Therefore, when selecting a vitamin C product it is important to pick a trustworthy source and be careful about the expiration date and proper storage.

If you are willing to invest a bit of extra time, you can easily make a vitamin C gel or serum on your own. That way you ensure both freshness and potency - not to mention substantial cost savings.

Even when using an optimal formulation, not everyone will respond to vitamin C treatments. About 50% of people show noticeable benefits. The chances are improved when vitamin C is a part of a comprehensive regimen to rebuild collagen in your skin. Also, people who do not respond to conventional vitamin C products may respond to its derivatives, such as magnesium ascorbyl phosphate, ascorbyl palmitate and others. These vitamin C cousins not only boost collagen synthesis but also are more stable and less irritating.

Finally, keep in mind that taking large amounts of vitamin C (or its derivatives) orally is of little benefit for reducing wrinkles because you cannot obtain high enough concentration of vitamin C in the skin to increase collagen production.



Herbs review : The benefits of Aloe vera as an antioxidant

Aloe vera have proactive vitamin complete enough that needed by the body , there are vitamins A, B1, B2, B3, B12, C, E, choline, inositol and folic acid. the mineral in Aloe are consist of calcium (Ca), magnesium (Mg), potasium (K), sodium (Na), iron (Fe), zinc (Zn) and chromium (Cr).

Fresh aloe vera leaves contain amilase enzyme, catalase, cellulase, carboxypeptidase, and others. In addition, aloe vera also contains a number of amino acid arginin, asparagin, aspartat acid, alanin, Serin, valin, glutamat, treonin, glisin, lisin, prolin, hisudin, leusin and isoleusin

Antioxidants
Some elements of vitamins and minerals can function as forming natural antioxidants such as vitamin C, vitamin E, vitamin A, magnesium, and zinc. Antioxidants are useful to prevent early aging, heart attack, and various degeneratif diseases. Potential subtances antioxidants have been successful isolated at this time from metanol extract of aloe vera (Aloe barbadensis Miller) with a combination of column chromatography techniques and thin layer chromatography . Analysis of in vitro using rat brain homogenat, shows that the antioxidants activity in the same compound with a strong, indicated by alfatokoferol (vitamin E).
Results show that the identification the substances classified into groups fenolic. Growth phase (age of harvest) appeared to influence the composition of the essential activities of antioxidants and aloe vera plant. Tests carried out on the concentration of antioxidants and the activities of the flavonoid compound and aloe vera polisakarida from the age of 2, 3, and 4 years. The results showed that aloe vera is the age of 3 years have polisaccharide and flavonoid contents greater than the age of 2 and 4 years.
Order antioxidants activity of each compared with the control, namely BHT (benzoyl hydroxytoluene) and alfatokoferol, sorted from the most powerful to the weak: aloe vera age 3 years> BHT> aloe vera age 4 years> alpha-tokoferol> aloe vera age 3 years show activities arrest of the most powerful free radical (72.19 percent) than BHT (70.52 percent) and alpha-tokoferol (65.20 percent) .
Elements that are found in the aloe vera leaves show the relationship of mutual synergistic in maintaining the integrity of the status of antioxidants in the body. Tests using mice that were given filtrate irradiasi leaf aloe vera juice as much as 0.25 ml / kg body weight / day, for 5 days before irradiattion and 10 days after irradiation, indicating the existence of a significant improvement of enzyme activity superoxide dismutase (SOD) and katalase on lung, kidney, and heart and katalase SOD enzyme is intracelluler and antioxidants that are beneficial to increase the body's immune system against various diseases. There is improvement in the decrease in GSH (glutation) is also shown in rats exposed to the rat-rays. In addition, aloe vera can also improve the effectiveness of transportation in the nutrition and oxygen to cells throughout the body so that the aloe vera can maintain the status of antioxidants in the body.

The Basic of Essential oil

Essential oil or oil eteris is a term used for the oil that is easy to evaporate, consisting of a mixture of substances that easily evaporate, with the composition and boiling point is different. Destilation can be defined as the separation of the components of a mixture of two or more types based on differences in vapor pressure.
Most of the Essentia oil compound consists of hydrocarbons and the hydrocarbons isocyclic that has oxygen binding fenol such as alcohol, ether and others. Essential oil contains a variety of different chemical components and can be classified into four groups, namely:
  • Terpena, related to isoprena,
  • Chain compound does not contain straight chain branches,
  • Benzena derivatives,
  • Various other compound
Essential oil is not a pure chemical substance, but consists of a mixture of various substances that have different physical-chemical. Boiling point components of oil easy to evaporate in the range of 1500 C-3000 C at 760mmHg pressure.
There are two types of destilasi, namely: water destillation and moisture destillation. To water destillation, materials that will destillate contact directly with boiling water. Materials float on the water or submerged in perfect depending on the type and amount of destillate heavy material . Characteristics of this method is direct contact between the materials with boiling water. Some of the things that we can know from the distillation of water, among others:
  • Type of distillation equipment simple, inexpensive, easily obtainable, easy to install in the areas of production.
  • Type of material used, especially the mashed, the flowers that is easy to cause the fumes directly. Less well adapt materials that contain constituents that can be soap and dissolved in water or boiling drip high.
  • Circumstances ranjangan form fine powder will give the best results.
  • Charging must be entirely submerged in water.
  • Diffusion take place either, if filled with a uniform material and can move freely in the boiling water.
  • Vapor pressure of about 1 atm, temperature 1000 C, arranged so that the distillation boiler is not too hot.
  • There is hidrolisa provide rendemen relatively low, because the constituents, the oil drip high boil water left behind in the distillation, and so forth.
Destilation advantage with this method, among others, is quite practical appliance, you can isolate the oil from the material in the powder, can be used for materials that cause if destillate with the steam, so that steam can not penetrated to the material. Losses of this method is some type of ester part will hidrolyzed , the sensitive compound such as aldehid experience polimerisation because the influence of water .

Welcome to herbal world

Hai,my name is dipta wana anandita. Im a student in pharmacy faculty for herbal science in Gadjah Mada University Indonesia. Just welcome to my blog that show you about the amazing of used herbal for health everyday.

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Drug Using in children and under five

The use of drugs in children and children under five is take more attention. Because the organs of children and children under five rudimentary development compared with adults, so children under five more sensitive to drugs. Children under five is not adults in a smaller size. So the use of drugs should not be indiscriminate. medicinal products that sell have been designed so the dose for children only and practical purpose more easy. As in the case where there is no medicine that is specially designed for children, or are available only for adults, better consultation on the doctor or pharmacist before use to be safe. Some of the medicines that need attention to be use for children under five and children include:

- Aspirin because aspirin it can cause Reye's syndrome
- Cloramphenikol because it can cause Gray baby syndrome
- Tetracyclin when used together with milk, can cause teeth to become yellow

While the drug is safe for children, among others, paracetamol for lower fever, as the antibiotic penicillin. Therefore, the use of drugs in children under five and children need to be consulted with medical team.

The healty pattern for children under five


When baby become children under five , they need the right nutrition and balanced nutrition. Because this is the age when body and the brain was growth rapidly. Age of five is the age-old who is very critical and therefore the nutrition Justify Fullyou provide to your baby need to be careful. What a useful nutrients to help growth and development of the brain and the body children under five? Let's see below.

Food provides energy and nutrition needed the baby so that it remains healthy. You should note that in this age-the age is:

• Make sure you baby under five get iron sufficient.

• Children aged 1-3 years need 500 mg of calcium per day

• Food that fibrous needed after 3 years because it can prevent disease.

• Before age 2 years, do not give your child nuts and seafood or seafood.

• At the age of 2-5 years, you can provide food-food such as rice, pasta, cereals, bread, corn, broccoli, cabbage flowers, carrots, potatoes, tomatoes, cassava, pumpkin, green vegetables, apples, bananas, citrus, strawberry, kiwi, watermelon, beef, chicken, fish, tofu, and of course milk and other dairy products.

• Avoid giving too much sugar to baby because sugar can make pancreas and kidneys work harder and can cause diabetes and Obesity. Change candy and food with sweet fruit and sweet tea with fruit juice that is not added sugar.

Depending on the age, activity and body size baby under five, they usually need around 1000 - 1400 calories per day. Each day, make sure they eat the rice (or pasta, cereals, bread for those who do not like rice), vegetables (make sure the software and properly cooked, so they do not choke), fruits, milk, meat (beef, fish, chicken) and beans. They need protein for 5-20% of daily calories, carbohydrates as much as 45-65% of calories each day (approximately 130 mg), total fat as much as 30-40% of calories each day, 1,000 milligram sodium per day, 19 grams of fiber a day and 500 mg of calcium per day.

Apart from food, you can ensure they get the nutrition they need to drink milk. Milk is rich in nutrients that help their growth, nutrition and also to help their brain development. And for your child that is difficult to eat, milk, nutrition can help to add that they do not get from food. Especially the development of the five most important for you is certainly healthy lifestyles. Give examples of healthy lifestyles for him and he will grow healthy, strong and intelligent.

so...still to uncare with the healty of your baby???thinking again!!

Effects of ginger on motion sickness and gastric slowwave dysrhythmias induced by circular vection

Written by :
HAN-CHUNG LIEN,1 WEI MING SUN,2 YEN-HSUEH CHEN,2 HYERANG KIM,2
WILLIAM HASLER,2 AND CHUNG OWYANG2
1Department of Internal Medicine, Division of Gastroenterology Taichung Veterans General
Hospital, National Yang-Ming University, Taipei, Taiwan; and 2Department of Internal
Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48019
Submitted 8 May 2002; accepted in final form 12 October 2002


Ginger has long been used as an alternative medication to prevent motion sickness. The mechanism of its action, however, is unknown. We hypothesize that ginger ameliorates the nausea associated with motion sickness by preventing the development of gastric dysrhythmias and the elevation of plasma vasopressin. Thirteen volunteers with a history of motion sickness underwent circular vection, during which nausea (scored 0-3, i.e., none to severe), electrogastrographic recordings, and plasma vasopressin levels were assessed with or without ginger pretreatment in a crossover-design, double-blind, randomized placebo-controlled study. Circular vection induced a maximal nausea score of 2.5 ± 0.2 and increased tachygastric activity and plasma vasopressin. Pretreatment with ginger (1,000 and 2,000 mg) reduced the nausea, tachygastria, and plasma vasopressin. Ginger also prolonged the latency before nausea onset and shortened the recovery time after vection cessation. Intravenous vasopressin infusion at 0.1 and 0.2 U/min induced nausea and increased bradygastric activity; ginger pretreatment (2,000 mg) affected neither. Ginger effectively reduces nausea, tachygastric activity, and vasopressin release induced by circular vection. In this manner, ginger may act as a novel agent in the prevention and treatment of motion sickness.

treatment; vasopressin

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